Antimetastatic Properties Of Aloe Juice
Gribel’ NV; Pashinskii VG
Vopr Onkol 32(12):38-40 1986

An evaluation of antimetastatic properties of succus Aloes was carried out using three types of experimental tumors of mice and rats. It was found that succus Aloes treatment contributes to reduction of tumor mass, metastatic foci and metastasis frequency at different stages of tumor progress without affecting major tumor growth. Succus Aloes potentiates the anti-tumor effect of 5-fluorouracil and cyclophosphamide as components of combination chemotherapy.

Effects Of Aloe Extracts On Human Normal & Tumor Cells In-Vitro
Winters WD; Benavides R; Clouse WJ
Dep. Microbiol., Univ. Tex. Health Sci. Center
Econ Bot 35 (1), 1981, 89-95

Fractions of leaf extracts from 2 local types, labeled Aloe vera (subsequently identified as A. barbadensis Mill., and A. saponaria Haw.), were prepared by differential centrifugation and tested by in vitro assays for the presence of lectin-like activities and for effects on the attachment and growth of human normal and tumor cells. Fractions of extracts of fresh leaves and commercially A. vera gel had high levels of lectin-like substances measured by immunodiffusion and nemagglutination assays. Substances in fluid fractions from both fresh leaf sources markedly promoted attachment and growth of human normal cells.

Epidemiologic Survey On Lung Cancer With Respect To Cigarette Smoking & Plant Diet
Sakai R
Department Of Epidemiology, School Of Health Sciences, Ryukyu University
Jpn J Cancer Res 80(6):513-20 1989 Jun

This case-control study of lung cancer was based on a cross-sectional questionnaire survey of inpatients at 5 general hospitals in Okinawa, Japan, from 1982 to 1987. The purpose of the study was to clarify the relations of lung cancer to cigarette smoking and plant diet. Ingestion frequencies of 17 major dietary plants and/or herbs were obtained by means of a questionnaire interview. As eligible subjects for a case-control analysis, there were 673 respondents aged over 30 years with clear smoking history, age, sex and diagnosis. Psychiatric patients were excluded. Odds ratios of newly diagnosed lung cancer were calculated by the Mantel-Haenszel procedure. A pair consisted of a case and two controls which were selected randomly by using multivariate caliper matching. Sixty-four pairs matched for age (+/- 5) and sex showed a significantly high odds ratio of 2.9 (P less than 0.0005). However, three male groups who were categorized by the number of cigarettes smoked did not exhibit dose-dependency of lung cancer on smoking. Lung cancer was more prevalent in exsmokers than in current smokers. Case-control analyses by male generations revealed that lung cancer incidence was age-dependent, and there was a clear dose-response relationship between smoking and lung cancer in males in their sixties. A case-control analysis of each of 17 edible plants based on 44 pairs who were matched for age (+/- 5), sex and smoking history demonstrated that the odds ratio of Aloe (Aloe arborescens Mill var. natalensis Berger) was 0.5 (P less than 0.1), suggesting that the Aloe may prevent human carcinogenesis at various sites.

Aloe Vera & AIDS Research

Various AIDS studies were completed by researchers such as Dr. Terry Pulse, M.D., Dr. Reg McDaniel, M.D., Dr. Terry Watson, D.O., Dr. Clumeck, M.D. (of Belgium) and others throughout the 1980’s using oral mucopolysaccharides. The results were impressive, demonstrating in many of the studies an average of 70% improvement in symptoms and laboratory criteria within 3 to 4 months. Many patients stated that opportunistic infections had stopped and they were able to return to normal activity. In one dramatic case, a man with advanced AIDS had 17 liver tumors and after one and a half years on oral Aloe mucopolysaccharides, his T-Cell count was normal and all the tumors had disolved (confirmed by x-ray films).

Lab studies showed that helper lymphocytes (CD4) rose to three times the pre-treatment levels. HIV-1 virus could no longer be cultured. P-24 antigen levels for the virus dropped or became negative.

Researchers at Vanderbilt Medical Center in Nashville, Tennessee discovered that Aloe mucopolysaccharides alters synthesis and thus the structure of the AIDS virus envelope necessary for infecting lymphocytes. Further studies at The Southern Research Institute found that there is suppression of the viral messenger RNA in HIV-1 infected leukocytes. Therefore, the reproduction of HIV-1 is inhibited with a natural and non-toxic substance.

In studies completed at the Fort Worth Medical Center Complex it was demonstrated that a person’s leukocytes were rendered resistant to HIV-1 virus in culture tests outside the body.